Abstract: A field experiment was conducted under rainfed conditions during kharif 2020 at Agricultural College Farm, University of Agricultural Sciences, Dharwad, to study the effect of different doses of herbicides and to evaluate their efficacy as tank-mixtures for weed control in maize. The trial consisted 12 treatments laid out in RCBD with three replications. The results indicated that tank mixture application of Ametryn @ 0.75 kg a.i. ha-1 + Topramezone @ 56.25 g a.i ha-1 resulted in higher weed control efficiency, lower weed dry weight, lowest weed density with higher seed yield and higher net returns. The results revealed that one time application of tank mix post emergence herbicides of Ametryn @ 0.5 kg a. i. ha-1 in combination with topramezone @ 56.25 g a. i. ha-1 25 days after sowing was found optimum for better weed management in maize resulting in to higher grian yield and net returns as compared to the present recommended practice