A field experiment was conducted at zonal Agricultural Research Station, Navile Shimoga, during kharif 2004 to study the leaf yield and nutrient uptake by FCV tobacco as influenced by levels of K and Mg.  Significantly highest cured leaf yield (1967 kg ha-1) and top grade equivalent (1188 kg ha-1) can be significantly improved by supply of 40 kg K2O ha-1 through pressmud + 40 kg K2O ha-1 through SOP at10 DAP with 15 kg MgO ha-1 due to synergistic effect of K and Mg. The highest content of K was found to be in leaves obtained from plots dressed with 40 kg K2O ha-1 through pressmud +40 kg K2O ha-1 through Sulfate of potash applied at 10 days after planting (3.55%). Among different nutrients absorbed from the soil, potassium was removed in highest amount by the tobacco crop (101.5 kg ha-1) indicating the importance of K in the mineral nutrient of flue cured tobacco plant.