Abstract : A field experiment was conducted at ICAR-KVK, University of Agricultural Sciences, Dharwad during rabi 2020 to develop suitable agro-techniques for chia (Salvia hispanica L). The experiment was laid out in split split plot design with three replications and twelve treatments. Treatments consists of three spacing (45 × 20 cm, 60 × 20 cm and 75 × 20 cm) as main plots, two methods of sowing (Line sowing and Transplanting) as sub plots, two fertilizer levels (30:20:20 kg and 60:40:40 kgN:P2O5 :K2O ha-1) as sub-sub plots. Spacing of 45 × 20 cm (S1 ) recorded significantly higher seed yield (797 kg ha-1), haulm yield (2960 kg ha-1), gross returns (` 1,59,462 ha-1), net returns (` 1,29,702 ha-1) and benefit cost ratio (5.36) compared to 60 × 20 cm (S2 ) and 75 × 20 cm (S3 ). Method of sowing had no significant influence on growth and yield parameters. However, line sowing (M1 ) recorded higher seed yield (722 kg ha-1) and haulm yield (2719 kg ha-1), gross returns (` 1,44,421 ha-1), net returns (` 1,14,640 ha-1) and B:C ratio (4.85) compared to transplanting (M2 ). Fertilizer level of (F1 ) 60:40:40 kg N:P2O5 :K2O ha-1 recorded significantly higher seed yield (744 kg ha-1) haulm yield (2766 kg ha-1), gross returns (` 1,48,845 ha-1), net returns (` 1,18,181 ha-1) and benefit cost ratio (4.85) compared to the application of (F2 ) 30:20:20 kg N:P2O5 :K2O ha-1. Interaction effects of (S1M1F2 ) recorded significantly higher seed yield (836 kg ha-1), net returns (`1,36,454 ha-1) and benefit cost ratio (5.44) of chia in Northern transition zone of Karnataka.