In a field experiment conducted on Typic Chromustert at Main Agricultural Research Station, University of Agricultural Sciences, Dharwad, the major and micro nurients uptake of chilli was significantly influenced by the effect of combined application of organic and inorganic source of nutrients. The highest uptake of major nutrients N (78.46 kg ha-1), P (16.69 kg ha-1), K (75.20 kg ha-1) and micronutrients Viz., Zn (119.69 g ha-1), Fe (367.18 g ha-1), Cu (48.91 g ha-1), Mn (103.71 g ha-1) were noticed with the application of 50 per cent RDN + 50 per cent N through FYM + BF + Panchagavya compared to other treatments. Significant difference existed among the treatments with respect to available nutrient (except K) status in soil. The highest available   major nutrients N ((324.9 kg ha-1), P (29.7 kg ha-1) and micronutrients, Zn (0.63 mg kg-1), Fe (3.88 mg kg-1), Cu (0.68 mg kg-1) and Mn (2.94 mg kg-1) were noticed with the application of 50 per cent RDN + 50 per cent N through FYM + BF + Panchagavya compared to other treatments. The combined use of organics (farmyard manure, vermicompost, biofertilizers, panchagavya) along with the inorganic fertilizers increased nutrient use efficiency, apparent nutrient recovery and the available nutrient status of the soil. Integrated use of organic manures along with chemical fertilizers not only produced highest and sustainable crop yields but also enhanced the efficiency of added fertilizers as well as fertility status of the soil.