A field experiment was conducted to study the effect of fertilizer levels and foliar nutrition on M-5 mulberry leaf nutrient status, quality and cocoon production. Nutrient status, quality and impact on cocoon parameters differed significantly over a period of two seasons. The pooled results indicated that maximum nitrogen, phosphorus and potassium content of mulberry leaf was obtained with 100 per cent RDF + foliar nutrition @ 2.0 per cent (2.79, 1.63 and 2.54% of NPK respectively). Maximum total sugar, reducing sugar, crude protein and chlorophyll content was recorded (31.68, 19.35, 17.43 mg g-1 and 35.94 Spad value respectively). Similarly, the maximum larval weight, cocoon weight, shell weight, shell ratio, productivity, minimum larval duration, highest cocoon yield was obtained. Leaf moisture content was not influenced by application of recommended dose of NPK fertilizer levels and foliar nutrition.