Bioefficacy of six insecticides and botanicals viz., dichlorvos 0.076%, acetamiprid 0.03%, triazophos 0.04%, thiomethoxam 0.025%, neem oil 3% and pungam oil 3% were evaluated against mulberry thrips, Pseudodentrothrips mori. Results of the four season trials show that among the chemicals, acetamiprid, thiomethoxam and dichlorvos were most effective recording lower thrips population levels of 0.73, 2.23 and 7.31 per leaf respectively, at 7DAT compared 62.70 per leaf in the untreated control. The order of efficacy of insecticides and botanicals is acetamiprid 0.03% > thiomethoxam 0.025% > dichlorvos 0.076% > triazophos 0.04% > neem oil 3% > pungam oil 3%. A bio-assay with insecticide and botanical- treated leaves on silkworm race PM x CSR 2 showed that no mortality was observed on 7th day for neem oil and pungam oil, on 10th day for dichlorvos. Triazophos and thiomethoxam were safer to silkworm on 15th day, whereas acetamiprid was safer on 20th day after spraying.