A laboratory experi ment was conducted to study the toxicity of various herbicides and iheir efficacy on saprophytic survival of Sclerotium rolfsii Sacc. Among the five hebricides evalu­ated in vitro, tribunit (meihabenzathtazuron) was found to inhibit ihe sclerotial germination-completely at 100 ppm while, isoproturon (3-(4-isopropyl phenyl)-!, 1-diamethyl Urea) and 2, 4-D Ethyl sodium salt (2, 4 dichloro Phenoxy acetic acid) were effective at 250 and 500 ppm respectively. Soil application of 0.4 per cent tribunil completely ceased the saprophytic acti­vity of the fungus.