Considering the presence of high variability in F₂ generation of safflower (Cartharms iinctoxius L-K selection was practiced for high seed yield in two crosses involving Indian X Indian parents and three crosses in voting Indian X exotic parents. Expected   response to selection was estimated and compared with the actual response obtained in F₄ generation. Due to selection exercised in all the five crosses in F₃ population, the expected grain for seed yield were actually realised to a consiberable extent in F₄ generation. Realised beritability generation. Realised heritability values were comparable to the broad sense heritability values observed in F₄.   Expected correlated response for almost all the characters were in agreement with the realized correlated response in F₄ generations.