An investigation was carried out to study the influence of cane regulation on fruit quality, pest and disease incidence in wine grapes (Vitis vinifera L.) during May 2009 to April 2010 in the vineyard of a progressive farmer in Bijapur district. Among the different cane regulation levels, vines regulated at 20 or 24 canes per vine produces the good quality grapes (TSS-23.73 OBrix, TSS to acid ratio-38.42, total sugars-22.49 %, reducing sugar of berries-20.80 % and minimum acidity-0.62 % and juice content of berries-70.59 %) for preparing quality wine, even though these treatments recorded lower yield than the control (no cane regulation) whereas, the varieties shows no significant difference regarding the yield and quality characters. The cane regulation treatments failed to influence the incidence of pest and disease incidence significantly.