The plant health management in agriculture is one of the dangerous unit operation which has led to serious problems in pesticide handling workers. But, they must work with pesticides for getting higher yields in agriculture. To prevent the operator against inhalation exposure to pesticides, the operator should wear the personal protective mask and other gadgets. In actual practice, majority of operators are not using these protective masks for various reasons. Therefore, a study was undertaken to evaluate commercially available masks for their materials of construction, filtering efficiency (Osha P.V. 2023 method), comfort while using in field (modified Corlett and Bishop scale) and breathing resistance were tested. The masks were found manufactured using foam pad, single and double layered poly propylene and cotton cloth as filtering materials. For preventing endosulfan inhaling from air, masks with double layered poly propylene with water repellent quality filter was found better with an average filtering efficiency of 87%. Operator’s opinion indicated that the mask made of flexible plastic with cotton filter and exhale valve gave an average wearing comfort and breathing comfort based on developed scale. The heat accumulation inside the mask was found to be on an average 10 per cent more in all the masks. The minimum breathing resistance was found in same mask as 0.68 m bar.