A Field experiment was conducted to study the response of genotypes to nutrient management practices on growth and yield of sugarcane. The experiment was laid out in split plot design with four nutrient supply systems viz., 100% organics (N1), 100% inorganics (N2), integrated nutrient management (INM) with 50% organics + 50% inorganics (N3) and recommended package of practices (RPP) (N4) as main plot treatments and three sugarcane genotypes viz., Co-92005 (G1), SNK-632 (G2) and Co-86032 (G3) as sub plot treatments with three replications. Among the different nutrient management practices, RPP recorded significantly higher green top (29.48 t ha-1), trash (6.33 t ha-1), cane (153.55 t ha-1) and total biomass (189.36 t ha-1) yield than N1 and N2. But, N3 was on par with N4. Similar trend was observed with respect to total dry matter production (TDMP) (379.61 g plant-1) and yield attributes like millable cane height (239.0 cm), cane diameter (3.40 cm), cane weight (1.60 kg cane-1) and millable cane number (97770 ha-1) at harvest. The cane yield reduced to the extent of 33.3 and 25.0 per cent in fully organic (N1) and fully inorganic (N2) treatments respectively, as compared to RPP. Among the genotypes, green top, trash, cane and total biomass yields were significantly higher in SNK-632 (28.40, 6.91, 156.47 and 191.78 t ha-1, respectively) than Co-86032 and Co-92005. Similarly, TDMP (408.26 g plant-1) and yield attributes like millable cane height (240.6 cm), cane diameter (3.35 cm), cane weight (1.61 kg cane-1) and millable cane number (1,09,970 ha-1) at harvest were higher in SNK-632 than Co-86032 and Co-92005. The genotype SNK-632 performed better with application of 100 per cent RDF (250:75:190 kg N:P2O5:K2O ha-1) along with FYM @ 25 t ha-1, Azosprillum and PSB @ 10 kg ha-1, FeSO4 and ZnSO4 @ 25 kg ha-1 (RPP) by recording higher cane (198.71 t ha-1) and total biomass (238.90 t ha-1) yield than other treatment combinations.