Climate change is a serious global environmental concern, which has led to increasing frequency of extreme weather events evident around the globe. Unusually heavy rain fall, which is due to climate change, is a significant cause of floods. Flood is the most destructive natural disaster which extensively damages livelihood. The present study was taken up to analyze impact of flood on livelihoods in Don river basin. Vijayapura district was purposively selected for the study based on the quantum of flood affected by farm economy in Don River basin in Vijayapura District, Karnataka. Flood affected households in severely affected villages were selected purposively on both banks of the River. Total size of the sample selected for the study was 240.  Simple statistical tools like averages and percentages were used in the study. Study revealed that floods caused huge loss to the cultivated land, farm inputs, crop yields, and stored grains, and livestock compared to a normal situation in the study area. To overcome these huge losses to society and to the individual households, Governments need to promote futuristic studies on climate variability and their specific impacts, take precautions measures in preventing the damges. In the post event, it is necessary to modify the norms for compensation to provide greater social security to the affected people. State and District level natural disaster management units should be strengthened with skilled manpower, advanced knowledge and logistic facilities to forecast accuatley and handle eventualities