Experiment comprised of five male sterile lines and nine testers of pearl millet and their 45 hybrids was conducted at Regional Agricultural Research Station, Vijayapur during kharif 2015, for studying the extent of hybrid vigour in F1 for grain yield and its components. For plant height, the cross combination ICMA 88004 x A5RLT 107, showed significant heterosis over mid parent and three checks used in the experiment. The hybrid ICMA 88004 x A5RLT 122, showed highest significant positive heterosis over the three checks for panicle length. Hybrid ICMA 00888 x A5RLT 106, showed highest significant mid parent and standard heterosis over the three checks for no. of productive tillers. The hybrid, ICMA 94555 x A5RLT 106 showed highest significant mid parent, better parent and standard heterosis over check GHB-558 towards positive direction for panicle girth (cm). The hybrid ICMA 81A x A5RLT 107, showed highest significant mid parent, better parent and standard heterosis over check GHB-558 for grain yield per hectare (kg/ha). While ICMA 81A x A5RLT 107, showed highest significant positive heterosis over the three checks used in the experiment for 1000 seed weight (gm).