Field experiments were conducted to study the performance of compact cotton genotypes under high densityplanting system and fertilizer levels during kharif 2014-15 and 2015-16 at University of Agricultural Sciences, Dharwad.The experiment was laid out in Strip-split plot Design with three replications. Genotypes, RAH-274, RAH-99 andDSC-1351 recorded significantly lower growth parameters (plant height, number of monopodial branches per plant andplant spread) and significantly higher dry matter production per plant, leaf area and leaf area index. Which were alsoproduced significantly higher yield attributes (number of sympodial branches per plant, number of bolls per plant and bollweight), seed cotton yield (3,199, 3,156 and 3,134 kg ha-1, respectively) and net returns (` 85,633, 83,845 and 82,899 ha-1,respectively) than DHG-7-96. Closer spacing of 45 × 10 cm (2,22,222 plants ha-1) recorded significantly higher seed cottonyield (3,372 kg ha-1) and net returns (` 92,678 ha-1) over other wider spacings. The application of higher dose of fertilizer(100:50:50 N, P2O5 and K2O kg ha-1) produced 5.42 per cent additional yield over lower dose of fertilizer. In interactioneffect, genotypes RAH-274, RAH-99 and DSC-1351 each sown at spacing of 45 × 10 cm with the application higher doseof fertilizer of 100:50:50 N, P2O5 and K2O kg ha-1 recorded significantly higher seed cotton yield (3,668, 3,575 and3,497 kg ha-1, respectively) and net returns (` 1,04,600, 1,00,701 and 97,411 ha-1, respectively).